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Home Antibody All anti-TNFRSF13C antibodies

Anti-TNFRSF13C Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306118
  • Rabbit Polyclonal BAFF Receptor Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC409380) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for TNFRSF13C (NM_052945)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenBAFF Receptor antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human BAFF Receptor The peptide sequence is identical between human and mouse origin.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2 - 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C)
Alternative NameBAFF-R; BAFFR; BROMIX; CD268; CVID4; prolixin
Database LinkNP_443177
Entrez Gene 115650 Human
Entrez Gene 72049 Mouse
Entrez Gene 500910 Rat
FunctionMembers in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4 (1-4). BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). Two receptors, TACI and BCMA, for BAFF were originally identified (5). A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3 (6,7). Unlike BCMA and TACI, which bind to BAFF and April, BAFF-R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kB and c-jun N-terminal kinase (4-6).
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interactionPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of BAFF Receptor in human (H), mouse (M), and rat (R) spleen tissue lysates with BAFF Receptor antibody at 5 ug/ml.
IHC Image
mmunohistochemistry of BAFF-R in human tonsil tissue with BAFF-R antibody at 5 ug/ml.

 

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