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Home Antibody All anti-TNF antibodies

Anti-TNF TRUEMAB Antibody Clone OTI1C1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA506513 TNF mouse monoclonal antibody, clone OTI1C1 (formerly 1C1) 100ul $325 In Stock
LC424626 TNF HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506513 Carrier-free (BSA/glycerol-free) TNF mouse monoclonal antibody, clone OTI1C1 (formerly 1C1) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IF(2)

OriGene Data

ImmunogenFull length human recombinant protein of human TNF(NP_000585) produced in HEK293T cell.
Clone NameClone OTI1C1 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:4000, IF 1:100,
Predicted MW Explanation 25.5 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens tumor necrosis factor (TNF)
Alternative NameDIF; TNF-alpha; TNFA; TNFSF2
Database LinkNP_000585
Entrez Gene 7124 Human
FunctionThis gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008].
Related PathwaySecreted ProteinTransmembraneTranscription FactorsDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionApoptosisTGF-beta signaling pathwayToll-like receptor signaling pathwayNOD-like receptor signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNF (RC206983, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TNF.
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Anti-TNF mouse monoclonal antibody (TA506513) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TNF(RC206983).
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Immunofluorescent staining of HeLa cells using anti-TNF mouse monoclonal antibody (TA506513).
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