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Anti-TNF TRUEMAB Antibody Clone 1C1
TrueMAB Antibodies - Made against Authentic Protein Antigens
|Full length human recombinant protein of human TNF(NP_000585) produced in HEK293T cell.|
|| WB 1:4000, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens tumor necrosis factor (TNF)|
|DIF; TNF-alpha; TNFA; TNFSF2|
|This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]. |
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TNF (RC206983, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TNF.
Anti-TNF mouse monoclonal antibody (TA506513) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TNF(RC206983).
Immunofluorescent staining of HeLa cells using anti-TNF mouse monoclonal antibody (TA506513).