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Home Antibody All anti-TNF antibodies

Anti-TNF Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300704
  • Rabbit Polyclonal Antibody against TNF
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424626) , 20ug
100ul 379 In Stock
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WB(1)
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Also for TNF (NM_000594)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA recombinant human TNF-a was used as an immunogen.
Clone Name IsotypeProtein A purified
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:5000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
Purification Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens tumor necrosis factor (TNF)
Alternative NameDIF; TNF-alpha; TNFA; TNFSF2
Database LinkNP_000585
FunctionTumor necrosis factor is a multifunctional proinflammatory cytokine, with effects on lipid metabolism, coagulation, insulin resistance, and endothelial function. Tumor necrosis factor-alpha (TNF-a), the product of activated monocytes, is secreted by macrophages in response to inflammation, infection and cancer (1). TNF-a triggers a signaling cascade, converging on the activation of the transcription factor NF-kappa B, which forms the basis for numerous physiological and pathological processes (2). TNF-a has been shown to play a role in systems such as the pathogenesis of psoriasis, tuberculosis, obesity, cerebral malaria, rheumatoid arthritis and asthma (3).
Related Pathway
Adipogenesis
Apoptosis
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
MAPK signaling pathway
TGF Beta Signaling Pathway
Toll-like receptor signaling pathway

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WB Image
Western blot - Anti-TNF alpha antibody; Anti-TNF alpha antibody at 1/5000 dilution + recombinant TNF alpha protein at 0.01 µg.Predicted band size : 25 kDa.Observed band size : 17.5 kDa .

 

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