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Home Antibody All anti-TMPRSS3 antibodies

Anti-TMPRSS3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303305
  • Goat Polyclonal Antibody against TMPRSS3
100ug 325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence C-EKIVYHSKYKPKR, from the internal region of the protein sequence according to NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:32,000. WB: 0.1-0.3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens transmembrane protease, serine 3 (TMPRSS3), transcript variant A
Alternative NameDFNB10; DFNB8; ECHOS1; TADG12
Database LinkNP_076927
Entrez Gene 64699 Human
Entrez Gene 140765 Mouse
FunctionThis gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Four alternatively spliced variants have been described, two of which encode identical products.
Related PathwayTransmembraneProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA303305 (0.1µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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