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Home Antibody All anti-TMPRSS2 antibodies

Anti-TMPRSS2 Antibody EPR3862

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307199
  • Rabbit monoclonal antibody against TMPRSS2(clone EPR3862)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401727) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for TMPRSS2 (NM_005656)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in the extracellular domain in human TMPRSS2 was used as an immunogen.
Clone NameEPR3862 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:500 - 1:1000; ICC: 1:500 - 1:1000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens transmembrane protease, serine 2 (TMPRSS2), transcript variant 2
Alternative NamePP9284; PRSS10
Database LinkNP_005647
FunctionTransmembrane protease, serine 2 (TMPRSS2) is a type-II transmembrane serine protease. It encodes a type II trans-membrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. The biological function of TMPRSS2 is unknown; however, seine proteases are known to be involved in many physiological and pathological processes (1). TMPRSS2 is expressed highly in primary and metastatic prostate cancers. It is also regulated by androgens and is associated with tumor cell differentiation (1, 2), making it a potential target for cancer therapy and diagnosis. TMPRSS2-ERG fusion, which occurs on account of translocations and interstitial deletions, is implicated in aggressive forms of prostate cancer (3, 4).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - TMPRSS2 antibody [EPR3862]; All lanes : Anti-TMPRSS2 antibody [EPR3862] at 1/1000 dilution.Lane 1 : Human prostate tissue lysate .Lane 2 : Human prostate tissue lysate .Lysates/proteins at 10 µg per lane.Predicted band size : 54 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TMPRSS2 antibody [EPR3862]; Immunohistochemical analysis of paraffin-embedded Human prostatic adenocarcinoma using TA307199 at a dilution of 1/500.

 

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