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Home Antibody All anti-TMEM59 antibodies

Anti-TMEM59 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319781
  • Rabbit Polyclonal TMEM59 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417690) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for TMEM59 (NM_004872)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTMEM59 antibody was raised against a 16 amino acid synthetic peptide near amino terminus of human TMEM59.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
BufferTMEM59 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification TMEM59 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens transmembrane protein 59 (TMEM59)
Alternative NameC1orf8; HSPC001
Database LinkNP_004863
FunctionTMEM59 Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TMEM59 in human kidney tissue lysate with TMEM59 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
IHC Image
Immunohistochemistry of TMEM59 in human kidney tissue with TMEM59 antibody at 2.5 ug/mL.
IF Image
Immunofluorescence of TMEM59 in human kidney tissue with TMEM59 antibody at 20 ug/mL.

 

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