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Anti-TMEFF2 Antibody EPR6386


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against TMEFF2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402517) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in the intracellular domain in human TMEFF2 was used as an immunogen.
Clone NameEPR6386 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsIHC-P: 1:50 - 1:100; ICC/IF: 1:50 - 1:100; FC: 1:10 - 1:100; WB: 1:1000 - 1:10000
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2), transcript variant 1
Alternative NameCT120.2; HPP1; TENB2; TPEF; TR; TR-2
Database LinkNP_057276
Entrez Gene 23671 Human
FunctionTMEFF2 is a survival factor for hippocampal and mesencephalic neurons (1). Soluble forms of TMEFF2’s extracellular domain have been reported to weakly stimulate erbB-4/HER4 tyrosine phosphorylation in gastric cancer cells, and they promote the survival of mesencephalic dopaminergic neurons. Elevated TMEFF2 expression is associated with higher prostate cancer grade and hormone independence (2). TMEFF2 is widely expressed in the brain, including hippocampal cornu ammonis, dentate gyrus, and substantia nigra pars compacta (1).
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-TMEFF2 antibody [EPR6386]; All lanes : Anti-TMEFF2 antibody [EPR6386] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : LnCaP cell lysate.Lane 3 : Caco 2 cell lysate.Lane 4 : SW480 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.developed using the ECL technique.Predicted band size : 41 kDa.
Other-Anti-TMEFF2 antibody [EPR6386](TA310900); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEFF2 antibody [EPR6386]; Immunohistochemical analysis of formailin-fixed, paraffin-embedded Human prostatic hyperplasia tissue staining TMEFF2 using TA310900 at a 1/50 dilution.


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