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Anti-TMEFF2 Antibody EPR6386
Also for TMEFF2 (NM_016192)
|A synthetic peptide corresponding to residues on the C-terminus in the intracellular domain in human TMEFF2 was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||IHC-P: 1:50 - 1:100; ICC/IF: 1:50 - 1:100; FC: 1:10 - 1:100; WB: 1:1000 - 1:10000
|pH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for IP.
|Homo sapiens transmembrane protein with EGF-like and two follistatin-like domains 2 (TMEFF2), transcript variant 1|
|CT120.2; HPP1; TENB2; TPEF; TR; TR-2|
Entrez Gene 23671 Human
|TMEFF2 is a survival factor for hippocampal and mesencephalic neurons (1). Soluble forms of TMEFF2’s extracellular domain have been reported to weakly stimulate erbB-4/HER4 tyrosine phosphorylation in gastric cancer cells, and they promote the survival of mesencephalic dopaminergic neurons. Elevated TMEFF2 expression is associated with higher prostate cancer grade and hormone independence (2). TMEFF2 is widely expressed in the brain, including hippocampal cornu ammonis, dentate gyrus, and substantia nigra pars compacta (1).|
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Western blot - Anti-TMEFF2 antibody [EPR6386]; All lanes : Anti-TMEFF2 antibody [EPR6386] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : LnCaP cell lysate.Lane 3 : Caco 2 cell lysate.Lane 4 : SW480 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.developed using the ECL technique.Predicted band size : 41 kDa.
Other-Anti-TMEFF2 antibody [EPR6386](TA310900); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TMEFF2 antibody [EPR6386]; Immunohistochemical analysis of formailin-fixed, paraffin-embedded Human prostatic hyperplasia tissue staining TMEFF2 using TA310900 at a 1/50 dilution.