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Anti-TLR2 Antibody EPR2078Y
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Also for TLR2 (NM_003264)
|A synthetic peptide corresponding to residues surrounding human TLR2 was used as an immunogen.|
||WB: 1:500; ICC: 1:250 - 500
|50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.|
|Homo sapiens toll-like receptor 2 (TLR2)|
|The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq]. |
Toll-like receptor signaling pathway
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Western blot analysis on THP-1 cell lysate using anti-TRL2 RabMAb (TA303828), dilution 1:500.