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Home Antibody All anti-TLR1 antibodies

Anti-TLR1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306266
  • Rabbit Polyclonal TLR1 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401125) , 20ug
100ug $325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenTLR1 antibody was raised against a peptide corresponding to 17 amino acids near the center of human TLR1.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, ICC: 10 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens toll-like receptor 1 (TLR1)
Alternative NameCD281; rsc786; TIL; TIL. LPRS5
Database LinkNP_003254
FunctionToll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5) so the organism can respond to potential infection. TLR1 is co-expressed with TLR2 on myeloid cells of the innate immune systems in lymphoid tissue such as monocytes and dendritic cells (6) where they form heterodimers that can recognize triacylated lipoproteins (7).
Related Pathway
Toll-like receptor signaling pathway

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WB Image
Western blot analysis of TLR1 in Daudi cell lysate with TLR1 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunocytochemistry of TLR1 in Daudi with TLR1 antibody at 10 ug/mL.

 

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