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Home Antibody All anti-TLE1 antibodies

Anti-TLE1 GAT Antibody Polyclonal

Generated by Genomic Immunization


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA590613 Rabbit Polyclonal TLE 1 Antibody 100ug $325 In Stock
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OriGene Data

ImmunogenDNA immunization. This antibody is specific for the Middle Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, ELISA Suggested DilutionsWB 1:20000, ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1), transcript variant 2
Alternative NameESG; ESG1; GRG1
Database LinkNP_005068
Entrez Gene 7088 Human
FunctionTLE 1 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. TLE 1 inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
Related PathwayTranscription Factors

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TLE1 (RC204037, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TLE1.

ELISA: TLE 1 Antibody


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