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Home Antibody All anti-TIMP2 antibodies

Anti-TIMP2 TRUEMAB Antibody Clone OTI1C4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA504312 TIMP2 mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) 100ul $325 In Stock
LC418809 TIMP2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504312 Carrier-free (BSA/glycerol-free) TIMP2 mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) 100ug $450 3-4 weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(2)
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Also for TIMP2 (NM_003255)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TIMP2(NP_003246) produced in HEK293T cell.
Clone NameClone OTI1C4 IsotypeIgG1
Species ReactivityHuman Concentration0.61 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:2000,
Predicted MW Explanation 21.7 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens TIMP metallopeptidase inhibitor 2 (TIMP2)
Alternative NameCSC-21K; DDC8
Database LinkNP_003246
Entrez Gene 7077 Human
FunctionThis gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq].
Related PathwaySecreted ProteinDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIMP2 (RC209796, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TIMP2.
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Western blot analysis of extracts (10ug) from 1 cell line by using anti-TIMP2 monoclonal antibody.(1:200)
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