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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-TIMP2 antibodies

Anti-TIMP2 TrueMAB Antibody clone 1A6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA504017
  • Purified TIMP2 mouse monoclonal antibody,clone 1A6
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418809) , 20ug
 100ul $325 In Stock Add to Shopping Cart
CF504017
  • Carrier-free (BSA/glycerol-free) TIMP2 mouse monoclonal antibody,clone 1A6
100ug $450 3-4 weeks Add to Shopping Cart
WB(2)
IHC(8)
FC(2)
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Also for TIMP2 (NM_003255)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens TIMP metallopeptidase inhibitor 2 (TIMP2)
Synonyms:CSC-21K
ImmunogenFull length human recombinant protein of human TIMP2(NP_003246) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Nameclone 1A6 IsotypeIgG1
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, FLOW 1:100,
BackgroundThis gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIMP2 (RC209796, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TIMP2.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TIMP2 monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-TIMP2 mouse monoclonal antibody. (TA504017)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-TIMP2 mouse monoclonal antibody. (TA504017)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TIMP2 mouse monoclonal antibody. (TA504017)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TIMP2 mouse monoclonal antibody. (TA504017)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-TIMP2 mouse monoclonal antibody. (TA504017)
IHC Image
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-TIMP2 mouse monoclonal antibody. (TA504017)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TIMP2 mouse monoclonal antibody. (TA504017)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-TIMP2 mouse monoclonal antibody. (TA504017)
FC Image
HEK293T cells transfected with either RC209796 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-TIMP2 antibody(TA504017), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-TIMP2 antibody(TA504017),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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