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Home Antibody All anti-TIMP1 antibodies

Anti-TIMP1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA309545 Goat Polyclonal Antibody against TIMP1 (aa129-143) 100ug $325 3-7 Days
LC418808 TIMP1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
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Also for TIMP1 (NM_003254)
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OriGene Data

ImmunogenPeptide with sequence C-NSLSLAQRRGFTKTY, from the internal region of the protein sequence according to NP_003245.1.
Clone Name Isotype
Species ReactivityTest: Human. Expected from seq similarity: Human, Dog, ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 0.1-0.3ug/ml
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Reference Data

Target NameHomo sapiens TIMP metallopeptidase inhibitor 1 (TIMP1)
Alternative NameCLGI; EPA; EPO; HCI; TIMP
Database LinkNP_003245
Entrez Gene 7076 Human
Entrez Gene 403816 Dog
FunctionThis gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq].
Related PathwaySecreted ProteinDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA309545 (0.1µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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