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Anti-TH TRUEMAB Antibody Clone OTI3H3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA506542 TH mouse monoclonal antibody, clone OTI3H3 (formerly 3H3) 100ul 325
In Stock
LC424777 TH HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506542 Carrier-free (BSA/glycerol-free) TH mouse monoclonal antibody, clone OTI3H3 (formerly 3H3) 100ug $450 8-10 Days
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OriGene Data

ImmunogenFull length human recombinant protein of human TH(NP_000351) produced in HEK293T cell.
Clone NameClone OTI3H3 IsotypeIgG2a
Species ReactivityHuman , Mouse Concentration1 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:400~4000, IF 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens tyrosine hydroxylase (TH), transcript variant 2
Alternative NameDYT14; DYT5b; TYH
Database LinkNP_000351
Entrez Gene 7054 Human
Entrez Gene 21823 Mouse
FunctionThe protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome Tyrosine metabolismMetabolic pathwaysParkinson's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TH (RC211218, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TH.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TH monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Anti-TH mouse monoclonal antibody (TA506542) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TH(RC211218).
Immunofluorescent staining of HeLa cells using anti-TH mouse monoclonal antibody (TA506542).


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