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Anti-TH Antibody EP1532Y
|A synthetic peptide corresponding to residues near the C-terminus of human Tyrosine 3-Hydroxylase was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:10000 - 1:50000; ICC: 1:100 - 1:250; FC: 1:20
|Preservative: 0.01% Sodium azide|
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for IHC-P or IP.
|Homo sapiens tyrosine hydroxylase (TH), transcript variant 2|
|DYT14; DYT5b; TYH|
Entrez Gene 7054 Human
Entrez Gene 21823 Mouse
Entrez Gene 25085 Rat
|The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq]. |
|Druggable Genome Tyrosine metabolismMetabolic pathwaysParkinson's disease|
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Western blot - Anti-Tyrosine Hydroxylase antibody [EP1532Y] - C-terminal; Anti-Tyrosine Hydroxylase antibody [EP1532Y] at 1/100000 dilution + PC12 cell lysate at 10 ug.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 58 kDa.