Home Antibody All anti-TGM2 antibodies
Also for TGM2 (NM_004613)
|Peptide with sequence C-ERDLYLENPEIKIR, from the internal region of the protein sequence according to NP_004604.2.|
|Test: Mouse, Rat. Expected from seq similarity: Human, Mouse, Rat, Pig, Cow
||Lot dependent; please refer to CoA along with shipment
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
|Homo sapiens transglutaminase 2 (TGM2), transcript variant 1|
|G-ALPHA-h; GNAH; HEL-S-45; TG2; TGC|
Entrez Gene 7052 Human
Entrez Gene 21817 Mouse
Entrez Gene 56083 Rat
|Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. |
|Druggable Genome Huntington's disease|
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TA309513 (1µg/ml) staining of Mouse Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.