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Home Antibody All anti-TGIF1 antibodies

Anti-TGIF1 TRUEMAB Antibody Clone 1H3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA802287
  • TGIF1 mouse monoclonal antibody,clone 1H3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC406653) , 20ug
100ul 325 In Stock
CF802287
  • Carrier-free (BSA/glycerol-free) TGIF1 mouse monoclonal antibody,clone 1H3
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
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Also for TGIF1 (NM_173208)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TGIF1 (NP_775300) produced in E.coli.
Clone NameClone 1H3 IsotypeIgG1
Species ReactivityHuman Concentration1.00 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:500,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens TGFB-induced factor homeobox 1 (TGIF1), transcript variant 3
Alternative NameHPE4; TGIF
Database LinkNP_775300
FunctionThe protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and eight variants, encoding four distinct isoforms, are described. [provided by RefSeq, Jul 2008].
Related Pathway
EGFR1 Signaling Pathway
TGF Beta Signaling Pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TGIF1 (RC201549, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TGIF1.

 

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