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Home Antibody All anti-TG antibodies

Anti-TG Antibody EPR3614

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307372
  • Rabbit monoclonal antibody against Thyroglobulin (clone EPR3614 )
100ul 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Thyroglobulin was used as an immunogen.
Clone NameEPR3614 IsotypeIgG
Species ReactivityHuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:10000 - 1:20000; IP: 1:50; IHC-P: 1:250 - 1:500; ICC/IF: Use at an assay dependent concentration
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens thyroglobulin (TG)
Alternative NameAITD3; TGN
Database LinkNP_003226
FunctionThyroglobulin (TG) is a dimeric glycoprotein specific to the thyroid gland which belongs to the type-B carboxylesterase/lipase family. It is the precursor of the iodinated thyroid hormones triiodothyronine (T3) and thyroxine (T4) (1, 2). Variations in TG are associated with susceptibility to autoimmune thyroid disease type 3 (2), and defective or impaired TG synthesis usually results in congenital goitrous hypothyroidism, virtual absence of TG in thyroid tissue, and the presence of an elevated concentration of iodoalbumin. The final result of these abnormalities is a decreased rate of T3 and T4 synthesis (3).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Thyroglobulin antibody [EPR3614]; Anti-Thyroglobulin antibody [EPR3614] at 1/10000 dilution + Human thyroid lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 305 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Thyroglobulin antibody [EPR3614]; TA307372, at a 1/2500 dilution, staining Thyroglobulin in paraffin embedded Human papillary thyroid carcinoma tissue by Immunohistochemisty.

 

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