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Home Antibody All anti-TEC antibodies

Anti-TEC Antibody Y398

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA303712 Rabbit monoclonal antibody against Tec(Y398) 100ul $325 2 Weeks
LC418830 TEC HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
FC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the PH domain of human Tec was used as immunogen.
Clone NameY398 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB: 1:2000 - 1:5000; IHC-P: Use at an assay dependent concentration; ICC: 1:100 - 1:250; FC: 1:30 - 1:100; IP: 1:50
Predicted MW Explanation 73 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Protein A purified

Reference Data

Target NameHomo sapiens tec protein tyrosine kinase (TEC)
Alternative NamePSCTK4
Database LinkNP_003206
Entrez Gene 100124696 Human
Entrez Gene 21682 Mouse
Entrez Gene 84492 Rat
FunctionThe protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome T cell receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Tec antibody [Y398]; Anti-Tec antibody [Y398] at 1/10000 dilution + Jurkat cell lysate.Predicted band size : 73 kDa.Observed band size : 66 kDa .
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Immunohistochemistry (Paraffin-embedded sections) - Tec antibody [Y398]; TA303712, at a 1/50 dilution,staining human ovary carcinoma by immunohistochemistry, Paraffin embedded tissue.
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Flow Cytometry - Anti-Tec antibody; Overlay histogram showing Jurkat cells stained with TA303712 (red line). The secondary antibody used was Alexa Fluor 488 goat anti-rabbit IgG (H+L) at 1:2000. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1ug/1x10^6 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control.
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