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Home Antibody All anti-TCF7L2 antibodies
UltraMAB

Anti-TCF7L2 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA590280
  • Rabbit Polyclonal TCF7L2 Antibody
100ug $325 3 Weeks
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WB(2)
IHC(2)
ELISA(1)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration0.98mg/ml
Guaranteed Application *WB, ELISA, IHC Suggested Dilutions WB 1:5000~20000, IHC 1:150,ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 2
Alternative NameTCF-4; TCF4
Database LinkNP_110383
Entrez Gene 6934 Human
Entrez Gene 21416 Mouse
Entrez Gene 679869 Rat
Entrez Gene 486894 Dog
FunctionThe TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.[supplied by OMIM]
Related PathwayTranscription FactorsDruggable Genome Wnt signaling pathwayAdherens junctionMelanogenesisPathways in cancerColorectal cancerEndometrial cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TCF7L2 (RC216058, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TCF7L2.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TCF7L2 polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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ELISA: TCF7L2 Antibody
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Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-TCF7L2 rabbit polyclonal antibody. (TA590280)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-TCF7L2 rabbit polyclonal antibody. (TA590280)
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