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Home Antibody All anti-TCF7L2 antibodies

Anti-TCF7L2 Antibody EP2033Y


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal Antibody against TCF7L2 (Clone EP2033Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403074) , 20ug Explanation
100ul $325 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart


OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human TCF-4 was used as an immunogen.
Clone NameEP2033Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB: 1:25000 - 1:100000; IP: 1:50; IHC-P: 1:100 - 1:250; FC: 1:50; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 68 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens transcription factor 7-like 2 (T-cell specific, HMG-box) (TCF7L2), transcript variant 2
Alternative NameTCF-4; TCF4
Database LinkNP_110383
Entrez Gene 6934 Human
Entrez Gene 21416 Mouse
Entrez Gene 679869 Rat
FunctionTCF4 (HMG box transcription factor 4) is a member of the lymphoid enhancer factor family of transcription factors. Essential during development, along with beta catenin and Bcl 9, TCF4 participates in the Wnt signaling thru transactivation of downstreams genes (1). Commonly found in intestinal epithelium, TCF4 is required in the maintenance of crypt stem cell compartments of small intestines (2). Mutation in TCF4 has implicated in colorectal cancer and high expression of TCF4 variants has been linked in increased risk of type II diabetes (3).
Related PathwayTranscription FactorsDruggable Genome Wnt signaling pathwayAdherens junctionMelanogenesisPathways in cancerColorectal cancerEndometrial cancerMore Pathways >>

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Western blot - TCF7L2 antibody [EP2033Y]; Anti-TCF7L2 antibody [EP2033Y] at 1/100000 dilution + Jurkat cell lysate at 10 ug.Secondary.goat anti-rabbit HRP at 1/1000 dilution.Predicted band size : 68 kDa.Observed band size : 68 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TCF7L2 antibody [EP2033Y]; TA301000 at 1/100 dilution staining T cell Transcription Factor 4 in human breast carcinoma by Immunohistochemistry, Paraffin-embedded tissue.
Immunocytochemistry/ Immunofluorescence - TCF7L2 antibody [EP2033Y]; TA301000 at 1/100 dilution staining T cell Transcription Factor 4 in HeLa cells by Immunofluorescence.
Flow Cytometry - Anti-TCF7L2 antibody [EP2033Y]; Overlay histogram showing Jurkat cells stained with TA301000 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody for 30 min at 22°C. The secondary antibody used was DyLight 488 goat anti-rabbit IgG (H+L) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1ug/1x10^6 cells) used under the same conditions. Acquisition of >5,000 events was performed.


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