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Home Antibody All anti-TCF7L2 antibodies

Anti-TCF7L2 Antibody EP2033Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA301000 Rabbit Monoclonal Antibody against TCF7L2 (Clone EP2033Y) 100ul $325 In Stock
LC403074 TCF7L2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human TCF-4 was used as an immunogen.
Clone NameEP2033Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB: 1:25000 - 1:100000; IP: 1:50; IHC-P: 1:100 - 1:250; FC: 1:50; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 68 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens transcription factor 7 like 2 (TCF7L2), transcript variant 2
Alternative NameTCF-4; TCF4
Database LinkNP_110383
Entrez Gene 6934 Human
Entrez Gene 21416 Mouse
Entrez Gene 679869 Rat
FunctionTCF4 (HMG box transcription factor 4) is a member of the lymphoid enhancer factor family of transcription factors. Essential during development, along with beta catenin and Bcl 9, TCF4 participates in the Wnt signaling thru transactivation of downstreams genes (1). Commonly found in intestinal epithelium, TCF4 is required in the maintenance of crypt stem cell compartments of small intestines (2). Mutation in TCF4 has implicated in colorectal cancer and high expression of TCF4 variants has been linked in increased risk of type II diabetes (3).
Related PathwayTranscription FactorsDruggable Genome Wnt signaling pathwayAdherens junctionMelanogenesisPathways in cancerColorectal cancerEndometrial cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - TCF7L2 antibody [EP2033Y]; Anti-TCF7L2 antibody [EP2033Y] at 1/100000 dilution + Jurkat cell lysate at 10 ug.Secondary.goat anti-rabbit HRP at 1/1000 dilution.Predicted band size : 68 kDa.Observed band size : 68 kDa.

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - TCF7L2 antibody [EP2033Y]; TA301000 at 1/100 dilution staining T cell Transcription Factor 4 in human breast carcinoma by Immunohistochemistry, Paraffin-embedded tissue.

IF Image
Immunocytochemistry/ Immunofluorescence - TCF7L2 antibody [EP2033Y]; TA301000 at 1/100 dilution staining T cell Transcription Factor 4 in HeLa cells by Immunofluorescence.

FC Image
Flow Cytometry - Anti-TCF7L2 antibody; Overlay histogram showing Jurkat cells stained with TA301000 (red line). The secondary antibody used was DyLight 488 goat anti-rabbit IgG (H+L) at 1:500. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1ug/1x10^6 cells) used under the same conditions. Acquisition of >5,000 events was performed.


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