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Home Antibody All anti-TCF3 antibodies

Anti-TCF3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306926
  • Rabbit Polyclonal TCF3 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC427823) , 20ug
100ug 325 In Stock
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WB(1)
IHC(1)
IF(1)
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Also for TCF3 (NM_001136139)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTCF3 antibody was raised against a 17 amino acid peptide near the amino terminus of human TCF3.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens transcription factor 3 (TCF3), transcript variant 2
Alternative NamebHLHb21; E2A; E47; ITF1; TCF-3; VDIR
Database LinkNP_001129611
FunctionThe TCF3 gene, also called E2A, encodes two basic helix-loop-helix (bHLH) transcription factors, E12 and E47, through alternative splicing. These transcription factors are involved in mediating canonical Wnt signaling, which is very important in a diverse array of cellular functions such as stem cell proliferation, self-renewal, activation, fate determination, differentiation and aging and senescence. They bind beta-catenin and can act as transcriptional activators or repressors for Wnt target genes, and have been shown to regulate specific target genes during CNS development downstream of Wnt signaling. TCF3/Lef complexes are also known to play key roles in controlling cell fate lineages in multipotent skin stem cells.
Related Pathway
Delta-Notch Signaling Pathway
Wnt Signaling Pathway

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WB Image
Western blot analysis of TCF3 in Human brain tissue lysate with TCF3 antibody at 1 ug/mL in (A) the absence and (B) presence of peptide blocking.
IHC Image
Immunohistochemistry of TCF3 in rat liver tissue with TCF3 antibody at 5 ug/mL.
IF Image
Immunofluorescence of TCF3 in rat brain tissue with TCF3 antibody at 20 ug/mL.

 

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