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Anti-TCF12 Antibody Polyclonal
Also for TCF12 (NM_003205)
|TCF12 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TCF12.|
|Human, Mouse, Rat
||ELISA, WB: 0.5 - 1 ug/ml, ICC: 10 ug/ml
|TCF12 Antibody is supplied in PBS containing 0.02% sodium azide.|
|TCF12 Antibody is affinity chromatography purified via peptide column.
|Homo sapiens transcription factor 12 (TCF12), transcript variant 3|
|bHLHb20; CRS3; HEB; HsT17266; HTF4|
|TCF12 Antibody: TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.|
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Western blot analysis of TCF12 in HeLa cell lysate with TCF12 antibody at (A) 0.5 and (B) 1 ug/mL.
Immunocytochemistry of TCF12 in HeLa cells with TCF12 antibody at 10 ug/mL.