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Anti-TBXAS1 TRUEMAB Antibody Clone OTI2C1
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for TBXAS1 (NM_001061)
|Full length human recombinant protein of human TBXAS1(NP_001052) produced in HEK293T cell.|
|WB, IHC, IF, FC
||WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens thromboxane A synthase 1 (platelet) (TBXAS1), transcript variant 1|
|BDPLT14; CYP5; CYP5A1; GHOSAL; THAS; TS; TXAS; TXS|
Entrez Gene 6916 Human
Entrez Gene 24886 Rat
|This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].|
|P450Druggable Genome Arachidonic acid metabolismMetabolic pathways|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TBXAS1 (RC208028, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TBXAS1.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TBXAS1 monoclonal antibody.
Figure from citation: Western Blot of TBXAS1(TxAS) protein level by using anti-TBXAS1 antibody in human lung adenocarcinoma. Dilution: 1:1000 View Citation
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-TBXAS1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501358, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-TBXAS1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501358, Dilution 1:50)
Anti-TBXAS1 mouse monoclonal antibody (TA501358) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TBXAS1(RC208028).
HEK293T cells transfected with either RC208028 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-TBXAS1 antibody(TA501358), and then analyzed by flow cytometry.
Flow cytometric Analysis of Hela cells, using anti-TBXAS1 antibody(TA501358),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
Flow cytometric Analysis of Jurkat cells, using anti-TBXAS1 antibody(TA501358),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).