Anti-TBK1 Phospho Antibody EPR2867(2)

SKU	Description	Amount	Price	Availability*
TA307115	Rabbit monoclonal antibody against NAK/TBK1 Phospho (pS172)(clone EPR2867(2)) (Phospho-Specific)	100ul	$325	In Stock
TA802519S	Purified GAPDH mouse monoclonal antibody (Loading control), clone 2D9	30ul	$100 $50*	In Stock

* Buy one primary antibody, get 50% off a GAPDH loading control antibody.

Also for TBK1 (NM_013254)

OriGene Data

Immunogen	A phospho specific peptide corresponding to residues surrounding serine 172 of human NAK/TBK1 was used as an immunogen. This antibody only detects NAK/TBK1 phosphorylated at serine 172.
Clone Name	EPR2867(2)	Isotype	Rabbit IgG
Species Reactivity	Human, Mouse, Rat	Concentration
Guaranteed Application *	WB	Suggested Dilutions	IP: 1:10 - 100, WB: 1:1,000 - 10,000,
Buffer	50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Purification	(Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens TANK-binding kinase 1 (TBK1)
Alternative Name	NAK; T2K
Database Link	NP_037386
Function	NFkappaB-activating kinase (NAK) also known as TANK binding kinase-1 (TBK1) or tumor necrosis factor receptor−associated factor 2-associated kinase (T2K) is a serine/threonine protein that belongs to the IkB kinase (IKK) family (1). Similar to IKK alpha and beta (2), NAK induces IkB degradation and NF-kB activity. NAK is activated by phorbol ester tumor promoters and growth factors, whereas catalytically inactive NAK specifically inhibits activation of NF-kB by protein kinase C-epsilon (PKCepsilon). NAK specifically phosphorylates IkB alpha on Serine 36 and NFkB subunit RelA (p65) on Serine 536 (3). NAK is also known to interact with TANK, TRAF-2 and TRIF (4).
Related Pathway	Toll-like receptor signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image

Western blot analysis on HeLa cell lysates using anti-Phospho-NAK/TBK1 (pS172) RabMAb .

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

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Anti-TBK1 Phospho Antibody EPR2867(2)

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data