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Home All anti-TBC1D4 antibodies
Anti-TBC1D4 Phospho Antibody EPR2733(2)
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for TBC1D4 (NM_014832)
OriGene Data
| A phospho specific peptide corresponding to residues surrounding Threonine 642 of human AS160 was used as an immunogen. This antibody only detects AS160 phosphorylated at Threonine 642. |
| EPR2733(2) |
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| Human |
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| WB |
WB: 1:1,000 - 10,000; |
| Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens TBC1 domain family, member 4 (TBC1D4) |
| AS160 |
| NP_055647 |
| AS160 is a Rab GTPase-activating protein (GAP) that is part of a subfamily of Rab GAPs that contain a conserved TBC1 (Tre-2/Bub2/Cdc16) domain (1). It is a negative regulator of GLUT4 vesicle translocation to the plasma membrane. The phosphorylation of TBC1D4 suppresses its GAP activity, thereby triggering docking of GLUT4 vesicles (2). AS160 is phosphorylated at multiple sites including Threonine 642. Insulin and IGF-1 induce 14-3-3 binding to AS160 mainly via phospho-Threonine 642 (3). |
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* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on 293T cell lysates using anti-Phospho-AS160 (pT642) RabMAb. Cells were either (A) untreated or (B) treated with insulin.
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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