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Home Antibody All anti-TAT antibodies

Anti-TAT GAT Antibody Polyclonal

Generated by Genomic Immunization


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA590802 Rabbit Polyclonal TAT Antibody 100ug $325 In Stock
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OriGene Data

ImmunogenDNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration0.86788 mg/ml
Guaranteed Application *ELISA Suggested DilutionsWB: 1:5000-1:20000; ELISA: 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens tyrosine aminotransferase (TAT)
Alternative Nametyrosine aminotransferase, cytosolic; tyrosine aminotransferase
Database LinkNP_000344
Entrez Gene 6898 Human
FunctionThe transcriptional transactivator (Tat) is a key regulatory protein of HIV. It is expressed early after the virus integrates into the cell, and stimulates the elongation of RNA polymerase II. It binds onto a sequence known as the TAR, or transactivator response element, located at the end of the HIV genetic chain. There, the tat protein helps assemble new copies of HIV. The tat protein-TAR complex speeds up the rate of viral reproduction by about a thousand times. If it is not present, the transcription process frequently stops short, and few functional HIV particles are produced.Tat is an important potential target for antiretrovirals and vaccine development.Transcriptional regulator that acts by binding to the trans-activating responsive sequence (TAR) RNA element and activates transcription initiation and/or elongation from the LTR promoter.
Related PathwayES Cell Differentiation/IPSEmbryonic stem cellsDruggable Genome Ubiquinone and other terpenoid-quinone biosynthesisCysteine and methionine metabolismTyrosine metabolismPhenylalanine metabolismPhenylalanine, tyrosine and tryptophan biosynthesisMetabolic pathwaysMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

ELISA: TAT Antibody


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