Home Antibody All anti-TARBP1 antibodies
Also for TARBP1 (NM_005646)
|TRBP1 antibody was raised against a 17 amino acid peptide from near the center of human TRBP1.|
||WB: 1 - 2 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens TAR (HIV-1) RNA binding protein 1 (TARBP1)|
|TRM3; TRP-185; TRP185|
Entrez Gene 6894 Human
|The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1alpha (EF-1alpha), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.|
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Western blot analysis of TRBP1 in 3T3 cell lysate with TRBP1 antibody at (A) 1 and (B) 2 µg/ml.