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Home Antibody All anti-TAB3 antibodies

Anti-TAB3 Antibody EPR5965

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310889
  • Rabbit Monoclonal antibody against TAB3
100ul $325 3-7 Days
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WB(1)
IF(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human TAB3 was used as an immunogen.
Clone NameEPR5965 IsotypeTissue culture supernatant
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, IF Suggested DilutionsWB: 1:1000 - 1:10000; ICC/IF: 1:50
BufferDoes not react with Rat. Is unsuitable for Flow Cyt,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens TGF-beta activated kinase 1/MAP3K7 binding protein 3 (TAB3)
Alternative NameMAP3K7IP3; NAP1
Database LinkNP_690000
FunctionTAB3 functions in the NF-kappaB signal transduction pathway. TAB3 and the similar and functionally redundant protein MAP3K7IP2/TAB2, form a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor (1).
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-TAB3 antibody [EPR5965]; All lanes : Anti-TAB3 antibody [EPR5965] at 1/1000 dilution.Lane 1 : 293T cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : Caco-2 cell lysate.Lane 5 : RAW264.7 cell lysate.Lane 6 : NIH 3T3 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 79 kDa.
Assay Image
Other-Anti-TAB3 antibody [EPR5965](TA310889); Equilibrium disassociation constant (KD)..
IF Image
Immunocytochemistry - Anti-TAB3 antibody [EPR5965]; TA310889, at 1/50 dilution, staining TAB3 in HepG2 cells by Immunofluorescence.

 

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