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Home Antibody All anti-IFIH1 antibodies

Anti-IFIH1 TRUEMAB Antibody Clone 8C10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA803667
  • IFIH1 (MDA5) mouse monoclonal antibody, clone 8C10
  • FREE positive control: HEK293T cell transient overexpression lysate (LC411723) , 20ug
100ul $325 In Stock
CF803667
  • Carrier-free (BSA/glycerol-free) IFIH1 mouse monoclonal antibody,clone 8C10
100ug $450 3-4 Days
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Also for IFIH1 (NM_022168)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human IFIH1 (NP_071451) produced in HEK293T cell.
Clone NameClone 8C10 IsotypeIgG1
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens interferon induced with helicase C domain 1 (IFIH1)
Alternative NameHlcd; IDDM19; MDA-5; MDA5; RLR-2
Database LinkNP_071451
FunctionDEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. [provided by RefSeq, Jul 2012].
Related Pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IFIH1 (RC215661, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IFIH1.

 

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