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Home Antibody All anti-UBE2D1 antibodies

Anti-UBE2D1 TRUEMAB Antibody Clone OTI1E7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA803633 UBE2D1 mouse monoclonal antibody, clone OTI1E7 (formerly 1E7) 100ul $325 In Stock
LC418756 UBE2D1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF803633 Carrier-free (BSA/glycerol-free) UBE2D1 mouse monoclonal antibody, clone OTI1E7 (formerly 1E7) 100ug $450 3 Days
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WB(1)
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Also for UBE2D1 (NM_003338)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human UBE2D1 (NP_003329) produced in E.coli.
Clone NameClone OTI1E7 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens ubiquitin-conjugating enzyme E2D 1 (UBE2D1), transcript variant 1
Alternative NameE2(17)KB1; SFT; UBC4/5; UBCH5; UBCH5A
Database LinkNP_003329
Entrez Gene 7321 Human
FunctionThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
Related Pathway Ubiquitin mediated proteolysis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UBE2D1 (RC205621, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UBE2D1.
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