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Anti-GBA TRUEMAB Antibody Clone OTI2B2
TrueMAB Antibodies - Made against Authentic Protein Antigens
|Human recombinant protein fragment corresponding to amino acids 40-315 of human GBA (NP_000148) produced in E.coli.|
|| WB 1:2000,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens glucosidase, beta, acid (GBA), transcript variant 1|
|GBA1; GCB; GLUC|
Entrez Gene 2629 Human
|This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]. |
|Druggable Genome Other glycan degradationSphingolipid metabolismMetabolic pathwaysLysosome|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GBA (RC216061, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GBA.
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-GBA mouse monoclonal antibody. (TA803376) Dilution: 1:150