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Home Antibody All anti-VEGFA antibodies

Anti-VEGFA TRUEMAB Antibody Clone OTI1A6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA803263 VEGFA mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) 100ul $325 In Stock
LC422435 VEGFA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF803263 Carrier-free (BSA/glycerol-free) VEGFA mouse monoclonal antibody, clone OTI1A6 (formerly 1A6) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
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Also for VEGFA (NM_001025366)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 206-412 of human VEGFA (NP_001020537) produced in E.coli.
Clone NameClone OTI1A6 IsotypeIgG2b
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 45.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens vascular endothelial growth factor A (VEGFA), transcript variant 1
Alternative NameMVCD1; VEGF; VPF
Database LinkNP_001020537
Entrez Gene 7422 Human
FunctionThis gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms. [provided by RefSeq, Jul 2008].
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionmTOR signaling pathwayVEGF signaling pathwayFocal adhesionPathways in cancerRenal cell carcinomaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY VEGFA (RC223789, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-VEGFA.
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