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Home Antibody All anti-BCL2 antibodies

Anti-BCL2 TRUEMAB Antibody Clone OTI2E5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA803003 BCL2 mouse monoclonal antibody, clone OTI2E5 (formerly 2E5) 100ul $325 In Stock
LC424602 BCL2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF803003 Carrier-free (BSA/glycerol-free) BCL2 mouse monoclonal antibody, clone OTI2E5 (formerly 2E5) 100ug $450 3 Days
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WB(2)
IHC(2)

OriGene Data

ImmunogenFull length human recombinant protein of human BCL2 (NP_000624) produced in E.coli.
Clone NameClone OTI2E5 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens B-cell CLL/lymphoma 2 (BCL2), transcript variant alpha
Alternative NameBcl-2; PPP1R50
Database LinkNP_000624
Entrez Gene 596 Human
FunctionThis gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008].
Related PathwayES Cell Differentiation/IPSTransmembraneStem cell - PluripotencyDruggable Genome ApoptosisFocal adhesionNeurotrophin signaling pathwayAmyotrophic lateral sclerosis (ALS)Pathways in cancerColorectal cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2 (RC204498, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2.
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Western blot analysis of extracts (10ug) from 7 different cell lines by using anti-BCL2 monoclonal antibody.(1:200)
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-BCL2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA803003)
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-BCL2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA803003)
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