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Home Antibody All anti-OAS2 antibodies

Anti-OAS2 TRUEMAB Antibody Clone OTI5E1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA802824 OAS2 mouse monoclonal antibody, clone OTI5E1 (formerly 5E1) 100ul $325 In Stock
LC400905 OAS2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF802824 Carrier-free (BSA/glycerol-free) OAS2 mouse monoclonal antibody, clone OTI5E1 (formerly 5E1) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(2)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 60-335 of human OAS2 (NP_002526) produced in E.coli.
Clone NameClone OTI5E1 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
Predicted MW Explanation 78.6 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens 2'-5'-oligoadenylate synthetase 2, 69/71kDa (OAS2), transcript variant 2
Alternative NameMGC78578
Database LinkNP_002526
Entrez Gene 4939 Human
FunctionThis gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OAS2 (RC208273, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OAS2.
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Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-OAS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802824)
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Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-OAS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA802824)
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