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Anti-HMBS TRUEMAB Antibody Clone OTI3E2
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for HMBS (NM_000190)
|Full length human recombinant protein of human HMBS (NP_000181) produced in HEK293T cell.|
|| WB 1:2000,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens hydroxymethylbilane synthase (HMBS), transcript variant 1|
|PBG-D; PBGD; PORC; UPS|
Entrez Gene 3145 Human
|This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]. |
|Druggable Genome Porphyrin and chlorophyll metabolismMetabolic pathways|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HMBS (RC201362, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HMBS.