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Home Antibody All anti-HMBS antibodies

Anti-HMBS TRUEMAB Antibody Clone OTI1F1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA802523 HMBS mouse monoclonal antibody, clone OTI1F1 (formerly 1F1) 100ul $325 In Stock
LC400069 HMBS HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF802523 Carrier-free (BSA/glycerol-free) HMBS mouse monoclonal antibody, clone OTI1F1 (formerly 1F1) 100ug $450 3 Days
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WB(2)

OriGene Data

ImmunogenFull length human recombinant protein of human HMBS (NP_000181) produced in HEK293T cell.
Clone NameClone OTI1F1 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 39.1 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens hydroxymethylbilane synthase (HMBS), transcript variant 1
Alternative NamePBG-D; PBGD; PORC; UPS
Database LinkNP_000181
Entrez Gene 3145 Human
FunctionThis gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome Porphyrin and chlorophyll metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HMBS (RC201362, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HMBS.
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Western blot analysis of  A549 cell lysate (35ug) by using anti-HMBS monoclonal antibody. Dilution: 1:500
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