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Home Antibody All anti-TYMS antibodies

Anti-TYMS TRUEMAB Antibody Clone 1A3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA801761
  • TYMS mouse monoclonal antibody,clone 1A3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC420700) , 20ug
100ul $325 In Stock
CF801761
  • Carrier-free (BSA/glycerol-free) TYMS mouse monoclonal antibody,clone 1A3
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(3)
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Also for TYMS (NM_001071)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TYMS (NP_001062) produced in E.coli.
Clone NameClone 1A3 IsotypeIgG1
Species ReactivityHuman Concentration1.00 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens thymidylate synthetase (TYMS)
Alternative NameHST422; TMS; TS
Database LinkNP_001062
FunctionThymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq, Jul 2008].
Related Pathway
Cell cycle

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TYMS (RC204814, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TYMS.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TYMS mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA801761)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-TYMS mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA801761)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-TYMS mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA801761)

 

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