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Home Antibody All anti-TYR antibodies

Anti-TYR TRUEMAB Antibody Clone OTI1F3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA801362 TYR mouse monoclonal antibody, clone OTI1F3 (formerly 1F3) 100ul $379 In Stock
LC424756 TYR HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF801362 Carrier-free (BSA/glycerol-free) TYR mouse monoclonal antibody, clone OTI1F3 (formerly 1F3) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IHC(1)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 19-320 of human TYR (NP_000363) produced in E.coli.
Clone NameClone OTI1F3 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
Predicted MW Explanation 58.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens tyrosinase (TYR)
Alternative NameATN; CMM8; OCA1; OCA1A; OCAIA; SHEP3
Database LinkNP_000363
Entrez Gene 7299 Human
FunctionThe enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008].
Related PathwayTransmembrane Tyrosine metabolismRiboflavin metabolismMetabolic pathwaysMelanogenesis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TYR (RC221797, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TYR.
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-TYR mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA801362)
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