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Anti-AMACR TRUEMAB Antibody Clone2A11
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for AMACR (NM_014324)
|Full length human recombinant protein of human AMACR (NP_055139) produced in HEK293T cell.|
|| WB 1:2000, IHC 1:150,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
|Homo sapiens alpha-methylacyl-CoA racemase (AMACR), transcript variant 1|
|AMACRD; CBAS4; RACE; RM|
|This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]. |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AMACR (RC213437, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-AMACR.
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-AMACR mouse monoclonal antibody. (TA800813)
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-AMACR mouse monoclonal antibody. (TA800813)