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RNA elements directing in vivo assembly of the 7SK/MePCE/Larp7 transcriptional regulatory snRNP Nucleic Acids Res., Mar 2013; 10.1093/nar/gkt159. [LA]

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Home All anti-MUC1 antibodies

Anti-MUC1 TrueMAB Antibody Clone 2E3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA800794
  • Purified MUC1 (EMA) mouse monoclonal antibody, Clone 2E3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC422694) , 20ug
100ul $379 In Stock Add to Shopping Cart
CF800794
  • Carrier-free (BSA/glycerol-free) MUC1 mouse monoclonal antibody,clone 2E3
100ug $450 8-10 Days Add to Shopping Cart
WB(2)
IHC(9)
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Also for MUC1 (NM_001018016)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens mucin 1, cell surface associated (MUC1), transcript variant 2
Synonyms:CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; PEM; PEMT; PUM
ImmunogenFull length human recombinant protein of human MUC1 (NP_001018016) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 2E3 IsotypeIgG2a
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000~4000, IHC 1:150,
BackgroundThis gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MUC1 (RC221390, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MUC1.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-MUC1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-MUC1 mouse monoclonal antibody. (TA800794)
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-MUC1 mouse monoclonal antibody. (TA800794)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-MUC1 mouse monoclonal antibody. (TA800794)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-MUC1 mouse monoclonal antibody. (TA800794)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-MUC1 mouse monoclonal antibody. (TA800794)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-MUC1 mouse monoclonal antibody. (TA800794)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-MUC1 mouse monoclonal antibody. (TA800794)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-MUC1 mouse monoclonal antibody. (TA800794)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-MUC1 mouse monoclonal antibody. (TA800794)

 

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