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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-CDH1 antibodies

Anti-CDH1 TrueMAB Antibody Clone1B11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA800718
  • Purified CDH1 (E Cadherin) mouse monoclonal antibody, Clone Clone 1B11
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401389) , 20ug
 100ul $325 In Stock Add to Shopping Cart
CF800718
  • Carrier-free (BSA/glycerol-free) CDH1 mouse monoclonal antibody,clone 1B11
100ug $450 3-4 weeks Add to Shopping Cart
WB(1)
IHC(10)
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Also for CDH1 (NM_004360)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens cadherin 1, type 1, E-cadherin (epithelial) (CDH1)
Synonyms:Arc-1; CD324; CDHE; ECAD; LCAM; UVO
ImmunogenFull length human recombinant protein of human CDH1 (NP_004351) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone1B11 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
BackgroundThis gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008].
Related Pathway
Adherens junction
Wnt Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH1 (RC220731, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH1.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-CDH1 mouse monoclonal antibody. (TA800718)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CDH1 mouse monoclonal antibody. (TA800718)
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-CDH1 mouse monoclonal antibody. (TA800718)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CDH1 mouse monoclonal antibody. (TA800718)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-CDH1 mouse monoclonal antibody. (TA800718)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-CDH1 mouse monoclonal antibody. (TA800718)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-CDH1 mouse monoclonal antibody. (TA800718)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CDH1 mouse monoclonal antibody. (TA800718)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-CDH1 mouse monoclonal antibody. (TA800718)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-CDH1 mouse monoclonal antibody. (TA800718)

 

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