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Anti-TICAM1 TRUEMAB Antibody Clone OTI1G7
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for TICAM1 (NM_182919)
|Human recombinant protein fragment corresponding to amino acids 120-420 of human TICAM1 (NP_891549) produced in E.coli.|
|Human , Monkey
|| WB 1:2000,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens toll-like receptor adaptor molecule 1 (TICAM1)|
|IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF|
Entrez Gene 148022 Human
Entrez Gene 574294 Monkey
|This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012]. |
|Druggable Genome Toll-like receptor signaling pathway|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TICAM1 (RC217522, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TICAM1.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-TICAM1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).