OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-CDH1 antibodies

Anti-CDH1 TRUEMAB Antibody Clone OTI1F3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA800671 CDH1 (E Cadherin) mouse monoclonal antibody, clone OTI1F3 (formerly 1F3) 100ul $379 In Stock
LC401389 CDH1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF800671 Carrier-free (BSA/glycerol-free) CDH1 mouse monoclonal antibody, clone OTI1F3 (formerly 1F3) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

spacer
WB(2)
IHC(3)

OriGene Data

ImmunogenFull length human recombinant protein of human CDH1 (NP_004351) produced in HEK293T cell.
Clone NameClone OTI1F3 IsotypeIgG1
Species ReactivityHuman , Dog Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000~4000, IHC 1:500,
Predicted MW Explanation 94.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cadherin 1, type 1, E-cadherin (epithelial) (CDH1)
Alternative NameArc-1; CD324; CDHE; ECAD; LCAM; UVO
Database LinkNP_004351
Entrez Gene 999 Human
Entrez Gene 442858 Dog
FunctionThis gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008].
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome Cell adhesion molecules (CAMs)Adherens junctionPathogenic Escherichia coli infectionPathways in cancerEndometrial cancerThyroid cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CDH1 (RC220731, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CDH1.
spacer
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CDH1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
spacer
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CDH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA800671)
spacer
Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-CDH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA800671)
spacer
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CDH1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA800671)
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title