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Home Antibody All anti-TIA1 antibodies

Anti-TIA1 TRUEMAB Antibody Clone OTI1A3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA800656 TIA1 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) 100ul $325 In Stock
LC411728 TIA1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF800656 Carrier-free (BSA/glycerol-free) TIA1 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)

OriGene Data

ImmunogenFull length human recombinant protein of human TIA1 (NP_071505) produced in HEK293T cell.
Clone NameClone OTI1A3 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 42.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens TIA1 cytotoxic granule-associated RNA binding protein (TIA1), transcript variant 2
Alternative NameTIA-1; WDM
Database LinkNP_071505
Entrez Gene 7072 Human
FunctionThe product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIA1 (RC219386, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TIA1.
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