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Home Antibody All anti-CUL4B antibodies

Anti-CUL4B TRUEMAB Antibody Clone OTI1C4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA800444 CUL4B mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) 100ul $379 In Stock
LC418558 CUL4B HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF800444 Carrier-free (BSA/glycerol-free) CUL4B mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IHC(4)
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Also for CUL4B (NM_003588)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-300 of human CUL4B (NP_003579) produced in E.coli.
Clone NameClone OTI1C4 IsotypeIgG2b
Species ReactivityHuman , Dog , Mouse Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:100,
Predicted MW Explanation 103.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cullin 4B (CUL4B), transcript variant 1
Alternative NameCUL-4B; MRXHF2; MRXS15; MRXSC; SFM2
Database LinkNP_003579
Entrez Gene 8450 Human
Entrez Gene 72584 Mouse
Entrez Gene 492102 Dog
FunctionThis gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Related Pathway Nucleotide excision repairUbiquitin mediated proteolysis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CUL4B (RC206935, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CUL4B.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CUL4B monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-CUL4B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800444)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-CUL4B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800444)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-CUL4B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800444)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-CUL4B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800444)
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