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Anti-SKIL TRUEMAB Antibody Clone OTI2F6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA800171 SKIL (SnoN) mouse monoclonal antibody, clone OTI2F6 (formerly 2F6) 100ul
30ul
$379 In Stock
LC417307 SKIL HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF800171 Carrier-free (BSA/glycerol-free) SKIL mouse monoclonal antibody, clone OTI2F6 (formerly 2F6) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
IHC(10)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 307-684 of human SKIL (NP_005405) produced in E.coli.
Clone NameClone OTI2F6 IsotypeIgG1
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:500~2000, IHC 1:150,
Predicted MW Explanation 76.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens SKI-like proto-oncogene (SKIL), transcript variant 1
Alternative NameSNO; SnoA; SnoI; SnoN
Database LinkNP_005405
Entrez Gene 6498 Human
Entrez Gene 20482 Mouse
Entrez Gene 114208 Rat
Entrez Gene 696680 Monkey
Entrez Gene 488159 Dog
FunctionThe protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Related PathwayTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SKIL (RC209251, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SKIL.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SKIL monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171)
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Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171)
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171)
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Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-SKIL mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800171)
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