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Anti-SPG7 TRUEMAB Antibody Clone OTI3H10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA800010 SPG7 mouse monoclonal antibody, clone OTI3H10 (formerly 3H10) 100ul 325
In Stock
LC401085 SPG7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF800010 Carrier-free (BSA/glycerol-free) SPG7 mouse monoclonal antibody, clone OTI3H10 (formerly 3H10) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 300-573 of human SPG7 (NP_003110) produced in E.coli.
Clone NameClone OTI3H10 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF, FC Suggested Dilutions WB 1:2000, IF 1:100, FLOW 1:100,
Predicted MW Explanation 88.1 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens spastic paraplegia 7 (pure and complicated autosomal recessive) (SPG7), transcript variant 1
Alternative NameCAR; CMAR; PGN; SPG5C
Database LinkNP_003110
Entrez Gene 6687 Human
FunctionThis gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq, Jul 2008].
Related PathwayTransmembraneProtease

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* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPG7 (RC206340, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPG7.
Anti-SPG7 mouse monoclonal antibody (TA800010) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPG7(RC206340).
Flow cytometric Analysis of Jurkat cells, using anti-SPG7 antibody(TA800010),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).


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