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Home Antibody All anti-PTGS2 antibodies
UltraMAB

Anti-PTGS2 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA590771 Rabbit Polyclonal COX2 Antibody 100ug $325 In Stock
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ELISA(1)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the C Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.83mg/ml
Guaranteed Application *ELISA Suggested DilutionsWB: 1:5000-1:20000; ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:250-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2)
Alternative NameCOX-2; COX2; GRIPGHS; hCox-2; PGG/HS; PGHS-2; PHS-2
Database LinkNP_000954
Entrez Gene 5743 Human
Entrez Gene 19225 Mouse
FunctionCOX2 (Cyclooxygenase-2. PGHS2) is an inducible dimeric enzyme belonging to prostaglandin G/H synthase family. COX2, similar to COX1, functions to form prostaglandins by catalyzing the synthesis of cyclic endoperoxides from arachidonic acid. COX2 expression is induced by lipopolysaccaride (LPS) and peptoglycan (PGN) and is highly expressed in activated marcophages. It has been implicated as a mediator of inflammation and a possible role in prostanoid signaling in activity-dependent plasticity (1). COX2 is considered as an ideal marker in immune response regulation studies and a therapeutic target against inflammatory diseases (2).
Related PathwayDruggable Genome Arachidonic acid metabolismVEGF signaling pathwayPathways in cancerSmall cell lung cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

ELISA: COX2 Antibody
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