Home Antibody All anti-DSG2 antibodies
Anti-DSG2 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for DSG2 (NM_001943)
|DNA immunization. This antibody is specific for the Middle Region of the target protein.|
|| WB 1:20000,ELISA 1:100-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens desmoglein 2 (DSG2)|
|ARVC10; ARVD10; CDHF5; CMD1BB; HDGC|
Entrez Gene 1829 Human
|Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 2 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines.|
|Transmembrane Arrhythmogenic right ventricular cardiomyopathy (ARVC)|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DSG2 (RC212294, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DSG2.